Seattle Seahawks at Indianapolis Colts: 2021 NFL Week 1 Pick

Seattle Seahawks (0-0) at Indianapolis Colts (0-0)

The Colts enter the season as one of the most banged up teams in the league. Both Carson Wentz and Quenton Nelson are expected to play after suffering foot injuries early in training camp and those are their two most important players, but they might not be at 100%, while left tackle Eric Fisher, top wide receiver TY Hilton, and top cornerback Xavier Rhodes are all out for at least this week with injury.

However, this line has shifted to compensate for that, as the Colts, once 1.5-point favorites, are now field goal underdogs at home against the Seahawks. I don’t like the Colts enough to bet on them, but they are the better side for pick ‘em purposes, as it’s a lot to ask even a strong team like the Seahawks to go on the road and win by more than a field goal against a Colts team that is still at least an average team, even with all of their injury issues.

Seattle Seahawks 24 Indianapolis Colts 23

Pick against the spread: Indianapolis +3

Confidence: Low

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