Tampa Bay Buccaneers (2-3) at San Francisco 49ers (1-5)
The 49ers are one of the worst teams in the league and there are very few teams I’d predict them to defeat, but I think the Buccaneers might be one. The Buccaneers enter in 28th in first down percentage differential and are very banged up. They’re missing their top-2 running backs, Doug Martin and Charles Sims, starting wide receiver Vincent Jackson, starting left guard JR Sweezy, starting defensive tackle Clinton McDonald, and top pass rusher Robert Ayers. With those players, this is one of the 5 least talented teams in the league.
That being said, the 49ers are probably still an inferior team (25th in first down percentage differential despite an easy schedule), so we’re not getting great a value with this even line. The 49ers get top cornerback Jimmie Ward back from injury this week, but lose starting running back Carlos Hyde on the offensive side of the ball. He’s been by far their most effective offensive weapon this season. I couldn’t be confident in the 49ers, but I am picking them to win their 2nd game of the season here at home against a banged up Tampa Bay team.
San Francisco 49ers 17 Tampa Bay Buccaneers 16
Pick against the spread: San Francisco PK