San Francisco 49ers at Seattle Seahawks: 2025 NFC Divisional Round Pick

San Francisco 49ers (13-5) at Seattle Seahawks (14-3)

This is the third time these two divisional opponents have met this season. The 49ers opened the season with a 17-13 win in Seattle week 1, in which the 49ers won the first down rate battle by 0.73 and the yards per play battle by 5.51%. In week 18, the Seahawks beat the 49ers in San Francisco 13-3, in a game in which the Seahawks won the first down rate battle by 11.90% and the yards per play battle by 1.27. Common sense would suggest that the more recent of the two matchups between these teams holds more predictive value and it is true that when two teams that split the season series meet for a third time in the post-season the team who won the more recent matchup tends to win more often than not, but maybe not as often as you would think, as teams are just 14-9 in that spot and just 11-12 ATS.

That alone isn’t a reason to pick the 49ers to cover, but I think this spread is a little inflated based on the recent matchup between these two teams, with the Seahawks favored by 7 points, after being favored by 2.5 points week 18. This game is in Seattle rather than San Francisco, but that much of a little movement is more than just the location change. The 49ers won’t have George Kittle for this game and the Seahawks will have left tackle Charles Cross, who didn’t play in the previous matchup, but the 49ers also get back left tackle Trent Williams, who is much better than Cross and more important to this offense than Kittle, and Kittle was not 100% in the previous matchup either. On top of that, the 49ers are likely to get back wide receiver Ricky Pearsall, who didn’t play in the previous matchup, though the loss of starting safety Ji’Ayir Brown does hurt them. Overall, I have this line calculated at Seattle -6, so we’re getting some line value with the 49ers, but not nearly enough for them to be worth betting.

Seattle Seahawks 20 San Francisco 49ers 14

Pick against the spread: San Francisco +7

Confidence: Low

Houston Texans at New England Patriots: 2025 AFC Divisional Round Pick

Houston Texans (13-5) at New England Patriots (15-3)

The Patriots enter this game with significant edges in first down rate differential (+3.36% vs. +1.93%) and yards per play differential (+1.10 vs. +0.48) compared to the Texans, which are both much more predictive than win/loss records. The Texans have faced a much tougher schedule, but, even when schedule is taken into account, the Patriots have about a 3-point edge in schedule adjusted efficiency, which is based on first down rate and yards per play differential. 

A big reason for that is schedule adjusted efficiency weights offensive performance higher than defensive performance, because offensive performance tends to be more consistent week-to-week. The Texans have a big edge on defense, about 5.5 points, but the Patriots have an even bigger edge on offense, about 7 points, and that tends to be more predictive of future winning. On top of that, the Texans have the biggest injury in this game, as their top wide receiver Nico Collins is expected to be out due to concussion, while the Patriots are close to fully healthy. Given all of that, this line is a little short, favoring the Patriots at home by only 3 points. My calculated line is Houston -5.5. There isn’t quite enough line value here for the Patriots to be worth betting, but they should be the right side for pick ‘em purposes.

New England Patriots 21 Houston Texans 16

Pick against the spread: New England -3

Confidence: Low