Philadelphia Eagles (1-0) at Indianapolis Colts (0-1)

The Eagles were down 17-0 early against the Jaguars last week at home, before coming back and winning 34-17. Their offense looked solid again, as it did last season with Nick Foles, but their defense continued to struggle. This line suggests these two teams are even, but I don’t think that’s the case right now as the Eagles’ offensive line is falling apart. Lane Johnson is still suspended. Allen Barbre, his replacement, is now out with an injury. Meanwhile, left guard Evan Mathis, one of the best offensive linemen in the league, was put on injured reserve with intent to return and will miss a significant period of time. The Eagles’ defense will continue to struggle and the offense won’t be as good with the offensive line banged up.

The Colts are also in the better spot here. Teams are 52-24 ATS as non-divisional home favorites before being divisional road favorites (in Jacksonville next week) since 2008. The Colts are also very good off of a loss and at home in the Andrew Luck era. They are 10-0 ATS off of a loss since Luck was drafted in 2012 and 11-5 ATS at home in that same time period. I like the Colts’ chances of beating a banged up Eagles team here in the first Monday Night Football game in Indianapolis in the Andrew Luck era.

Indianapolis Colts 31 Philadelphia Eagles 20

Pick against spread: Indianapolis -3

Confidence: Medium

[switch_ad_hub]

[switch_ad_hub]

[switch_ad_hub]